| hydrazid; isoniazid; isonicotinic acid hydrazide; isonicotinic hydrazide; isonicotinohydrazide; isonicotinyl hydrazide; pyridine-4-carbohydrazide; 4-pyridinecarboxylic acid hydrazide; rimifon | |
| Links: | 🌍 Wikipedia, ⚗️ ChemSynthesis, 📖 PubMed |
| MeSH: | Anti-Infective Agents; Antitubercular Agents |
| CAS RN: | [54-85-3] |
| Formula: | C6H7N3O; 137.14 g/mol |
| InChiKey: | QRXWMOHMRWLFEY-UHFFFAOYSA-N |
| SMILES: | NNC(=O)c1ccncc1 |
| Toxicology (LD50): | 51.0 mg/Kg (dog, iv); 200 mg/Kg(guinea~pig, ip); 200 mg/Kg(guinea~pig, or); 203 mg/Kg(mouse, ct); 132 mg/Kg(mouse, ip); 159 mg/Kg(mouse, ip); 150 mg/Kg(mouse, iv); 152 mg/Kg(mouse, iv); 165 mg/Kg(mouse, iv); 171 mg/Kg(mouse, iv); 142 mg/Kg(mouse, or); 190 mg/Kg(mouse, or); 205 mg/Kg(mouse, or); 160 mg/Kg(mouse, sc); 170 mg/Kg(mouse, sc); 203 mg/Kg(mouse, sc); 95.0 mg/Kg(rabbit, iv); 250 mg/Kg(rabbit, or); 500 mg/Kg(rat, ip); 650 mg/Kg(rat, or); 1 435 mg/Kg(rat, or) |
| Melting point: | 171 °C |
| Log10 partition octanol / water: | -0.70 |